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Fiacre's First and Foremost
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Fiacre's First and Foremost : ウィキペディア英語版
Fiacre's First and Foremost

Ch. Fiacre's First and Foremost (born 9 September 2007), also known as Fiona, is a Dalmatian bred to have low levels of uric acid. She is registered to the United Kennel Club Dalmatian Breed Club in America and was registered with the American Kennel Club in 2011, when LUA Dalmatians were granted entry into the AKC. She became the first low uric acid Dalmatian to compete at Crufts in the United Kingdom in 2011.
==Background and early life==
Dr. Robert Schaible started a breeding program in 1973 to outcross an American Kennel Club (AKC) champion Dalmatian with a Pointer to correct a genetic defect in the Dalmatian breed that affects the metabolism of uric acid. This condition can lead to a variety of complications, including urate crystal arthropathy, bladder stones, obstruction of the urinary tract and potentially death.
Fiona was born on September 9, 2007, in Nevada,〔 her unique breeding name being "Fiacre's First and Foremost".〔 She has liver spots. She is the 15th generation of the cross conducted by Dr. Schaible, which makes her 99.98% Dalmatian.
She has been tested for the mutated gene that causes high uric acid levels, and the results showed she carried the normal genes for uric acid levels. Dogs with a single normal gene will have low levels of uric acid, but their offspring can have either high or low levels of uric acid; however, dogs like Fiona who have two normal genes have low uric acid levels and all of their offspring will have low levels of uric acid, regardless of the dog to which it is bred.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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